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Synthesis of Printed Hollow Fiber Membranes Urea as a Membrane Candidate Hemodialysis

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Abstract

Chronic kidney failure is a disease that affects the world's population and an alternative solution is hemodialysis. Hemodialysis is the process of cleaning the blood from urea and creatinine through a semi-permeable membrane in the form of a hollow fiber membrane (HFM) with the following advantages: flexible and low energy requirements. The weaknesses of commercial hemodialysis membranes are that they are hydrophobic, chemical resistant, and low biocompatibility. This research uses a membrane of polysulfone combined with eugenol and polyethylene glycol (PEG) or polyethylene glycol diglycidyl ether (PEGDE). Eugenol has allyl, hydroxy, and methoxy groups which are derived from polyeugenol via allyl groups and from polyeugenol to polyeugenoxy acetic acid via hydroxyl groups. The resulting molecularly imprinted membrane (MIM) in the form of hollow fiber has better porosity, absorption, flux values and is highly selective in transport, with the order of selectivity, namely urea > creatinine > vitamin B12.

Original languageEnglish
Pages (from-to)1583-1601
Number of pages19
JournalIndonesian Journal of Chemistry
Volume24
Issue number6
DOIs
Publication statusPublished - 2024

Keywords

  • hemodialysis
  • hollow fiber
  • imprinted
  • polyeugenoxy acetate

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